Population 1,633,216 in city. Guadalajara is the capital of the state of Jalisco. It is considered the most Mexican city in Mexico and is arguably the best planned and most beautiful city in the country. Guadalajara is one of the most important cultural and artistic centers in Mexico. Almost every cultural trait associated with Mexico originated in or near Guadalajara including Tequila (Tequila, Jalisco) and Mariachi music (Cocula, Jalisco).